Product Description

Acidic Fibroblast Growth Factor

Human, recombinant (OsraFGF)

CAS Number: **********8

Category Number: HY**4M1

Biological Source: Oryza Sativa (Rice Grain)

Physical Appearance:  Lyophilized Powder

Synonyms:

aFGF; FGF*1, retina-derived growth factor, heparin-binding growth factor (class I or alpha), astroglial growth factor I

Introduction:

Fibroblast Growth Factor-Acidic (aFGF) is a potent mitogenic agent for a wide variety of mesoderm-derived cells including BALB/c 3T3 fibroblasts, capillary and endocardial endothelial cells, myoblasts, vascular smooth muscle cells, mesothelial cells, glial and astroglial cells, and adrenal cortex cells.1,2 In cells not growth inhibited by heparin (such as baby hamster kidney cells), heparin potentiates the actions of aFGF, but in cells inhibited by heparin (such as bovine brain-derived capillary endothelial cells), no such potentiation is observed.

Application :

1. Medicine and clinical research:

 It is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

2. Cosmetic raw material:

a) Anti-wrinkle, Anti-oxidant, Skin whitening: 

aFGF modulates the skin rejuvenating by kstimulation of cell proliferation ;

Rejuvenates both the epidermal cells and the underlying fibroblast cells, which produce collagen, elastin, and hyaluronic acid, maintain human skin elasticity, and decrease cutaneous senescence;

The proliferation of epidermal cells enhanced the skin cells regeneration.

b) Rejuvenates hair follicle to produce new hair;
aFGF can activate FGF*7, promote hair growth by stimulation of cell proliferation on primary hair cell, treat or prevent baldness.

Usage:

For Research, Laboratory and Manufacture Use. The product should not be used as drugs and food additives.